CSI: Crime Scene Investigation Season 11 Episode 5 (CSI s11e05) with title “House of Hoarders” aired on Thursday, October 21st 2010 at 09:00 pm via CBS Network.
Here is summary for CSI: Crime Scene Investigation Season 11 Episode 5 :

A woman who suffers from a condition called “hoarding” becomes a murder suspect when a dead body is found buried under piles of trash and debris inside her home.