The Simpsons Season 22 Episode 2 (The Simpsons s22e02) with title “Loan-a-Lisa” aired on Sunday, October 3rd 2010 at 08:00 pm via FOX Network.
Here is summary for The Simpsons Season 22 Episode 2 :

Lisa invests in Nelson’s new business, which becomes an instant success, but cautions him against dropping out of school as a result. Nobel Peace Prize winner Muhammad Yunus and Facebook founder Mark Zuckerberg have voice cameos as themselves.